compound 4b [PMID: 19683441]

Ligand id: 7755

Name: compound 4b [PMID: 19683441]

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 68.95
Molecular weight 494.21
XLogP 4.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
MCH1 receptor Hs Antagonist Antagonist 8.3 pIC50 - 1
pIC50 8.3 (IC50 4.79x10-9 M) [1]