Ligand id: 7769

Name: florbetaben    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 12
Topological polar surface area 39.72
Molecular weight 359.19
XLogP 4.46
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
amyloid β Hs None Binding 8.6 pKi - 2
pKi 8.6 (Ki 2.22x10-9 M) PET imaging agent for Aβ plaques in brain [2]
Description: Inhibition of 18F-AV-45 binding to Aβ plaques in postmortem AD brain homogenates.