Ligand id: 8005

Name: OSU-03012

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 72.42
Molecular weight 460.15
XLogP 5.68
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
3-phosphoinositide dependent protein kinase 1 Hs Inhibitor Inhibition 8.1 pIC50 - 3
pIC50 8.1 (IC50 9x10-9 M) [3]