Ligand id: 8317

Name: azeliragon

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 14
Topological polar surface area 39
Molecular weight 531.27
XLogP 8.8
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
advanced glycosylation end-product specific receptor Hs Antagonist Antagonist ~6.0 pIC50 - 3-4
pIC50 ~6.0 (IC50 ~1x10-6 M) [3-4]