Ligand id: 8322

Name: ML290

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 109.95
Molecular weight 506.11
XLogP 5.71
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP1 Hs Allosteric modulator Agonist 7.0 pEC50 - 1-2
pEC50 7.0 (EC50 9.4x10-8 M) [1-2]
Ligand mentioned in the following text fields