A(C10/15S)INSL3   Click here for help

GtoPdb Ligand ID: 8331

Comment: Synthetic analogue of human INSL3, comprising an A and a B chain. The sequence of the B chain is the same as that of natural ligand and is shown on the ligand page for INSL3 (B chain), while the sequence of the A chain is shown on the 'structure' tab. The reference describing the synthesis of this peptide includes a figure respresenting the structure including disulphide bond formation between the chains.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP2 Hs Antagonist Antagonist 8.6 pKi - 1
pKi 8.6 [1]