minimised relaxin-3 analogue 2   Click here for help

GtoPdb Ligand ID: 8336

Comment: A synthetic analogue of human relaxin-3 comprising a synthetic truncated from of the A chain, and a B chain matching the natural sequence of relaxin-3 B chain. The sequence of the A chain can be found from the link on the structure tab of this ligand page, and please see the ligand entry for relaxin-3 (B chain) for the sequence of the B chain. N.B. The truncated A chain subunit of this peptide is also a subunit of minimised relaxin-3 analogue 3.
Click here for help
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP3 Hs Agonist Full agonist 7.9 pKi - 1
pKi 7.9 [1]
RXFP4 Hs Agonist Full agonist 7.1 pKi - 1
pKi 7.1 [1]
RXFP3 Hs Agonist Full agonist 8.4 – 10.4 pEC50 - 1
pEC50 8.4 – 10.4 [1]
RXFP4 Hs Agonist Full agonist 7.7 pIC50 - 1
pIC50 7.7 [1]