Ligand id: 8427

Name: relenopride

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 119.91
Molecular weight 492.19
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT4 receptor Hs Agonist Partial agonist 8.3 pKi - 3
pKi 8.3 (Ki 4.96x10-9 M) [3]
5-HT2B receptor Hs Agonist Agonist 7.5 pKi - 3
pKi 7.5 (Ki 3.1x10-8 M) [3]
5-HT2A receptor Hs Agonist Agonist 6.2 pKi - 3
pKi 6.2 (Ki 6x10-7 M) [3]