Ligand id: 8463

Name: amelubant

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 100.87
Molecular weight 538.25
XLogP 8.45
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Bioactivity Comments
As a prodrug, amebulant has very little affinity for the BLT1 receptor [1]. Bioactivity is attributed to its active metabolite, BIIL 260.