Ligand id: 8463

Name: amelubant

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 100.87
Molecular weight 538.25
XLogP 8.45
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

1. Birke FW, Meade CJ, Anderskewitz R, Speck GA, Jennewein HM. (2001)
In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist.
J. Pharmacol. Exp. Ther., 297 (1): 458-66. [PMID:11259574]