MK-7725

Ligand id: 8502

Name: MK-7725

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 139.06
Molecular weight 615.1
XLogP 6.3
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
BB3 receptor Hs Agonist Agonist 8.5 pIC50 - 1
pIC50 8.5 (IC50 3x10-9 M) [1]