Ligand id: 8502

Name: MK-7725

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 139.06
Molecular weight 615.1
XLogP 6.3
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Chobanian HR, Guo Y, Liu P, Chioda M, Lanza Jr TJ, Chang L, Kelly TM, Kan Y, Palyha O, Guan XM et al.. (2012)
Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
ACS Med Chem Lett, 3 (3): 252-6. [PMID:24900461]