PF-01247324

Ligand id: 8521

Name: PF-01247324

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 68.01
Molecular weight 328.99
XLogP 3.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Nav1.8 Hs Channel blocker Pore blocker 6.7 pIC50 - 1
pIC50 6.7 (IC50 1.96x10-7 M) [1]