MT47-100

Ligand id: 8821

Name: MT47-100

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 93.81
Molecular weight 345.1
XLogP 5.7
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
protein kinase AMP-activated non-catalytic subunit beta 1 Hs Activator Activation 5.4 pKi - 1
pKi 5.4 (Ki 3.7x10-6 M) [1]
protein kinase AMP-activated non-catalytic subunit beta 2 Hs Allosteric modulator Negative 4.6 pKi - 1
pKi 4.6 (Ki 2.48x10-5 M) [1]