Ligand id: 8985

Name: adriforant

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 79.1
Molecular weight 262.19
XLogP 1.61
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
H4 receptor Hs Antagonist Antagonist 8.3 pKi - 2
pKi 8.3 [2]
H3 receptor Hs Antagonist Antagonist 6.7 pKi - 2
pKi 6.7 [2]
Ligand mentioned in the following text fields