bihelical apoA-I mimetic peptide 5A

Ligand id: 9183

Name: bihelical apoA-I mimetic peptide 5A

Structure and Physico-chemical Properties

2D Structure
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Bioactivity Comments
In vitro, the 5A peptide was able to solubilize phospholipid vesicles and stimulated cholesterol and phospholipid efflux by the ABCA1 transporter with high specificity but no affinity data has yet been reported [4].
Selectivity at transporters
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
ABCA1 Hs None Binding - - - 3
The 5A sequence was able to solubilize phospholipid vesicles and stimulated cholesterol and phospholipid efflux by the ABCA1 transporter with high specificity but no specific binding data was reported [3]