Lys[Z(NO2)]-Val   Click here for help

GtoPdb Ligand ID: 9486

Comment: A side chain modified dipeptide inhibitor of PepT1 (Peptide transporter 1 / SLC15A1) [2].
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Selectivity at transporters
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Peptide transporter 2 Hs Inhibitor Inhibition 7.0 pKi - 1,4
pKi 7.0 [1,4]
Peptide transporter 1 Hs Inhibitor Inhibition 5.7 pKi - 2-3
pKi 5.7 (Ki 2x10-6 M) [2-3]
Description: Competition assays in Caco-2 cells expressing PEPT1.