Lys[Z(NO2)]-Val   Click here for help

GtoPdb Ligand ID: 9486

Comment: A side chain modified dipeptide inhibitor of PepT1 (Peptide transporter 1 / SLC15A1) [2].
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References
1. Biegel A, Knütter I, Hartrodt B, Gebauer S, Theis S, Luckner P, Kottra G, Rastetter M, Zebisch K, Thondorf I et al.. (2006)
The renal type H+/peptide symporter PEPT2: structure-affinity relationships.
Amino Acids, 31 (2): 137-56. [PMID:16868651]
2. Knütter I, Hartrodt B, Theis S, Foltz M, Rastetter M, Daniel H, Neubert K, Brandsch M. (2004)
Analysis of the transport properties of side chain modified dipeptides at the mammalian peptide transporter PEPT1.
Eur J Pharm Sci, 21 (1): 61-7. [PMID:14706812]
3. Theis S, Knutter I, Hartrodt B, Brandsch M, Kottra G, Neubert K, Daniel H. (2002)
Synthesis and characterization of high affinity inhibitors of the H+/peptide transporter PEPT2.
J Biol Chem, 277 (9): 7287-92. [PMID:11751927]