AZD2098

Ligand id: 9678

Name: AZD2098

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 89.56
Molecular weight 332.97
XLogP 2.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
AZD2098 is devoid of agonist activity up to a concentration of 10 μM [1]
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCR4 Mm Antagonist Antagonist 8.0 pIC50 - 1
pIC50 8.0 (IC50 1x10-8 M) [1]
CCR4 Rn Antagonist Antagonist 8.0 pIC50 - 1
pIC50 8.0 (IC50 1x10-8 M) [1]
CCR4 Hs Antagonist Antagonist 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.58x10-8 M) [1]
CCR4 Clf Antagonist Antagonist 7.6 pIC50 - 1
pIC50 7.6 (IC50 2.51x10-8 M) [1]