Ligand id: 9678

Name: AZD2098

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 89.56
Molecular weight 332.97
XLogP 2.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
AZD2098 inhibits CCR4-mediated chemotaxis in response to the endogenous CCR4 agonists CCL22 and CCL17 [1]. Anti-inflammatory acivity has been demonstrated in Brown-Norway rats.