stanozolol   Click here for help

GtoPdb Ligand ID: 10369

Synonyms: Stromba® | Tevabolin® | WIN-14833 | WIN14833 | Winstrol®
Approved drug
stanozolol is an approved drug (FDA (1962))
Compound class: Synthetic organic
Comment: Stanozolol is a synthetic, orally active steroid that has anabolic and androgenic properties [3]. Chemically, it is a 17α-alkylated derivative of dihydrotestosterone. It has low binding affinity for the androgen receptor, but is a strong activator of androgen receptor-induced protein synthesis and erythropoietin production [1].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 48.91
Molecular weight 328.25
XLogP 5.86
No. Lipinski's rules broken 1
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Canonical SMILES CC12Cc3cn[nH]c3CC1CCC1C2CCC2(C1CCC2(C)O)C
Isomeric SMILES C[C@]12Cc3cn[nH]c3C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(C)O)C
InChI InChI=1S/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1
No information available.
Summary of Clinical Use Click here for help
Stanozolol is no longer marketed in the USA, but retains approval in other countries. Medical use in humans includes treatment of hereditary angioedema and other vascular disorders. Stanozolol is a WADA anti-doping catergory 'S1-Anabolic Agent' that is banned by a number of sporting bodies as it is has been exploited as a performance-enhancing drug. It is also a veterinary medicine.
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