Synonyms: AAI101 | OCID-5090
enmetazobactam is an approved drug (FDA (2024))
Compound class:
Synthetic organic
Comment: Enmetazobactam is an extended-spectrum β-lactamase inhibitor. It is an N-methylated tazobactam derivative. It is intended for use alongside β-lactamase antimicrobials, to reduce their degradation.
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No information available. |
Summary of Clinical Use |
Cefepime + enmetazobactam was evaluated for efficacy in the treatment of complicated urinary tract infections [1]. The combination (Exblifep®) was FDA approved for this indication in February 2024 and has also been recommended for approval by the EMA (January 2024). |
Clinical Trials | |||||
Clinical Trial ID | Title | Type | Source | Comment | References |
NCT03687255 | Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections | Phase 3 Interventional | Allecra | 2 |