Synonyms: Deltyba® | OPC-67683
delamanid is an approved drug (EMA (2014))
Compound class:
Synthetic organic
Comment: Delamanid is a nitro-dihydro-imidazooxazole derivative with potent antibacterial activity against mycobacteria [1-2]. This drug is used in the treatment of multidrug-resistant tuberculosis (MDR-TB).
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No information available. |
Mechanism Of Action and Pharmacodynamic Effects |
Delamanid inhibits the biosynthesis of mycolic acid, an essential component of the cell wall of M. tuberculosis (IC50 of 0.021-0.036 μg/ml) [1]. |
External links |
For extended ADME data see the following: European Medicines Agency (EMA) |