Synonyms: amiodarone hydrochloride | Cordarone®
amiodarone is an approved drug (FDA (1985))
Compound class:
Synthetic organic
Comment: Amiodarone is a class III antiarrhythmic drug and acts as a positive inotropic agent. The prescription drug contains amiodarone hydrochloride (PubChem CID 441325).
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖![]() View more information in the IUPHAR Pharmacology Education Project: amiodarone |
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No information available. |
Summary of Clinical Use ![]() |
Used to treat angina and arrhythmias. |
Mechanism Of Action and Pharmacodynamic Effects ![]() |
Principally an ion channel blocker acting on sodium and potasium channels. It also appears to have β-blocker-like action (via β-adrenoceptors). |
External links ![]() |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com |