Ligand id: 2634

Name: triiodothyronine

Abbreviated name: T3

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 650.79
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat patients with hypothyroidism as a replacement or supplemental therapy.
Mechanism Of Action and Pharmacodynamic Effects
T3 increases the basal metabolic rate, affects protein synthesis and increases sensitivity to catecholamines including adrenaline.
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