Ligand id: 2634

Name: triiodothyronine

Abbreviated name: T3

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 92.78
Molecular weight 650.79
XLogP 2.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Friesema EC, Kuiper GG, Jansen J, Visser TJ, Kester MH. (2006)
Thyroid hormone transport by the human monocarboxylate transporter 8 and its rate-limiting role in intracellular metabolism.
Mol. Endocrinol., 20 (11): 2761-72. [PMID:16887882]
2. Nguyen NH, Apriletti JW, Cunha Lima ST, Webb P, Baxter JD, Scanlan TS. (2002)
Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment.
J. Med. Chem., 45 (15): 3310-20. [PMID:12109914]