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Synonyms: penicillin G sodium | penicillin-G potassium
penicillin G is an approved drug (FDA (1947))
Compound class: Synthetic organic
Comment: Penicillin G (benzylpenicillin ) is a narrow spectrum penicillin antibiotic.
Penicillin G is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|No information available.|
|Summary of Clinical Use|
|Used in the treatment of severe bacterial infections including septicemia, meningitis, pericarditis, endocarditis and severe pnuemonia.|
|Mechanism Of Action and Pharmacodynamic Effects|
|Binds to specific penicillin-binding proteins in the bacterial cell wall which inhibits the last stage of bacterial cell wall synthesis.|
For extended ADME data see the following: