penicillin G

Ligand id: 4796

Name: penicillin G

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 112.01
Molecular weight 334.1
XLogP 1.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of severe bacterial infections including septicemia, meningitis, pericarditis, endocarditis and severe pnuemonia.
Mechanism Of Action and Pharmacodynamic Effects
Binds to specific penicillin-binding proteins in the bacterial cell wall which inhibits the last stage of bacterial cell wall synthesis.
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