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Synonyms: penicillin G sodium | penicillin-G potassium
penicillin G is an approved drug (FDA (1947))
Compound class: Synthetic organic
Comment: Penicillin G (benzylpenicillin ) is a narrow spectrum penicillin antibiotic.
Penicillin G is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Transporters Moving this Compound Across a Lipid Membrane|
|Targets where the ligand is described in the comment field|
|Peptide transporter 1||A variety of dipeptides and drugs interact with PEPT1, including carnosine , D-Phe-Ala [7,13], D-Phe-Gln , 5-aminolevulinic acid [15-17], nateglinide , glibenclamide , valacyclovir [2-4,9], cefadroxil , cephalexin  and penicillin G (benzylpenicillin) , as detected using [3H] and [14C] radio-labelled probes.|
|Peptide transporter 2||Other high-affinity (non-transported) inhibitors: Lys[Z(NO2)]-Val (Ki 2 μM) [12-13], Lys[Z(NO2)]-Pro (Ki 3-7 μM) [12-13]; other low-affinity, (non-transported) inhibitors: 4-AMBA (Ki 3 mM) [1,6,14]. Like PEPT1, PEPT2 interact with dipeptides and drugs including carnosine , D-Phe-Ala [7,20], 5-aminolevulinic acid [7,11,15-17], nateglinide , glibenclamide , cefadroxil , cephalexin  and penicillin G (benzylpenicillin) .|