Synonyms: acyclovir | Zovirax®
aciclovir is an approved drug (FDA (1982, prior history not available))
Compound class:
Synthetic organic
Comment: Aciclovir is a nucleoside analogue antiviral drug.
Aciclovir is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019). |
|
No information available. |
Mechanism Of Action and Pharmacodynamic Effects ![]() |
Aciclovir is a guanosine analogue and is converted by host cell kinases to aciclovir triphosphate (ACV-TP), which then competitively inhibits and inactivates viral DNA polymerases [2] and is incorporated into viral DNA [1,3]. This action halts viral replication. |