Ligand id: 6011

Name: mubritinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 11
Topological polar surface area 65.97
Molecular weight 468.18
XLogP 5.37
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Mubritinib completed a Phase 1 clinical trial in patients with HER2+ve solid tumours (NCT00034281), but development has not progressed further.