Ligand id: 6810

Name: dorzolamide

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 151.33
Molecular weight 324.03
XLogP -0.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Dorzolamide is used in ophthalmic solutions to lower intraocular pressure in open-angle glaucoma and other conditions involving ocular hypertension.
Mechanism Of Action and Pharmacodynamic Effects
A carbonic anhydrase inhibitor which decreases aqueous humor secretion.