Synonyms: AL-6221 | Travatan®
travoprost is an approved drug (EMA and FDA (2001))
Compound class:
Synthetic organic
Comment: Travoprost is an analogue of prostaglindin F2α (PGF2α). The drug itself is a prodrug that is hydrolysed in vivo to an active free acid form.
View more information in the IUPHAR Pharmacology Education Project: travoprost |
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No information available. |
Summary of Clinical Use |
Used to decrease elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
Mechanism Of Action and Pharmacodynamic Effects |
Travoprost free acid is a selective FP prostanoid receptor (PTGFR) agonist, which reduces intraocular pressure by increasing the outflow of aqueous fluid from the eye. |
External links |
For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com European Medicines Agency (EMA) |