carprofen   Click here for help

GtoPdb Ligand ID: 7141

Synonyms: Ro-205720000
Approved drug Immunopharmacology Ligand
carprofen is an approved drug
Compound class: Synthetic organic
Comment: Carprofen is a non-steroidal anti-inflammatory drug (NSAID), although it is no longer marketed for human use and now seems to be used exclusively by vets.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 53.09
Molecular weight 273.06
XLogP 3.79
No. Lipinski's rules broken 0
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Canonical SMILES OC(=O)C(c1ccc2c(c1)[nH]c1c2cc(cc1)Cl)C
Isomeric SMILES OC(=O)C(c1ccc2c(c1)[nH]c1c2cc(cc1)Cl)C
InChI InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)
No information available.
Summary of Clinical Use Click here for help
Used in veterinary practice to relieve pain, inflammation and sewlling, including that in arthritic or deteriorating joints, and that experienced post-operatively.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
This drug reduces prostaglandin synthesis by reducing cyclooxegenase 1 (COX1) activity.