Ligand id: 7356

Name: cerlapirdine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 83.67
Molecular weight 409.15
XLogP 4.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
The phase 2 trial for Alzheimer's disease NCT00895895 for SAM-531 was stopped due to lack of efficacy at a 6-month review.