Synonyms: AMR-101 | icosapent ethyl | icosapentate | Vascepa® | Vazkepa®
icosapent is an approved drug (FDA (2012), EMA (2021))
Compound class:
Synthetic organic
Comment: Icosapent is a synthetic ethyl ester derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is de-esterified during absorption to active EPA that is absorbed in the small intestine.
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No information available. |
Summary of Clinical Use ![]() |
Approved to treat patients with severely high triglyceride levels (hypertriglyceridemia) [1-2], in conjunction with a low-fat and low-cholesterol diet. |
Mechanism Of Action and Pharmacodynamic Effects ![]() |
The molecular mechanism whereby icosapent reduces triglyceride levels is poorly understood and is likely multifactorial. |
External links ![]() |
For extended ADME data see the following: Drugs.com |