Ligand id: 7614

Name: trimethobenzamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 69.26
Molecular weight 388.2
XLogP 2.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Trimethobenzamide is prescribed to treat and prevent nausea and vomiting caused by gastroenteritis or other illnesses [1], medications or surgery [2].
Mechanism Of Action and Pharmacodynamic Effects
The precise MMOA of this drug remains elusive, but it is believed to affect the chemoreceptor trigger zone (CTZ) of the medulla oblongata.
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