Ligand id: 7614

Name: trimethobenzamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 69.26
Molecular weight 388.2
XLogP 2.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Friedman BW, Hochberg M, Esses D, Bijur PE, Corbo J, Paternoster J, Solorzano C, Toosi B, Lipton RB, Gallagher EJ. (2006)
A clinical trial of trimethobenzamide/diphenhydramine versus sumatriptan for acute migraines.
Headache, 46 (6): 934-41. [PMID:16732839]
2. Sheiner B. (1960)
Use of Trimethobenzamide (Tigan) in Anesthesia.
Can Med Assoc J, 83 (26): 1377-8. [PMID:20326574]