Ligand id: 7883

Name: CP-724714

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 98.26
Molecular weight 469.21
XLogP 3.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
CP-724714 had potential for treating HER2 +ve breast cancer. The only Phase II clinical trial assessing the compound for this indication (NCT00102895) was terminated and development appears to have stopped.