CP-724714

Ligand id: 7883

Name: CP-724714

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 98.26
Molecular weight 469.21
XLogP 3.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
erb-b2 receptor tyrosine kinase 2 Hs Inhibitor Inhibition 7.9 pIC50 - 1
pIC50 7.9 (IC50 1.2x10-8 M) [1]