acenocoumarol   Click here for help

GtoPdb Ligand ID: 9015

Synonyms: Sinthrome® | Sintrom®
Approved drug
acenocoumarol is an approved drug
Compound class: Synthetic organic
Comment: Acenocoumarol is a coumarin that is used as an anticoagulant, with actions and uses similar to warfarin. The coumarins are vitamin K epoxide reductase antagonists.
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View more information in the IUPHAR Pharmacology Education Project: acenocoumarol

2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 110.65
Molecular weight 353.09
XLogP 3.49
No. Lipinski's rules broken 0
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Canonical SMILES CC(=O)CC(c1c(=O)oc2c(c1O)cccc2)c1ccc(cc1)[N+](=O)[O-]
Isomeric SMILES CC(=O)CC(c1c(=O)oc2c(c1O)cccc2)c1ccc(cc1)[N+](=O)[O-]
InChI InChI=1S/C19H15NO6/c1-11(21)10-15(12-6-8-13(9-7-12)20(24)25)17-18(22)14-4-2-3-5-16(14)26-19(17)23/h2-9,15,22H,10H2,1H3
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Summary of Clinical Use Click here for help
Acenocoumarol does not appear to have US FDA or EMA approval, but is approved by individual national regulatory agencies worldwide. Approved as an anticoagulant.