carotuximab   Click here for help

GtoPdb Ligand ID: 9098

Synonyms: c-SN6j | TRC-105 | TRC105
Compound class: Antibody
Comment: Carotuximab is an investigational, chimeric mouse/human anti-endoglin monoclonal antibody, with potential immunomodulatory and antineoplastic action.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. Protein BLAST analysis reveals 100% matches with peptides claimed in patent US8221753, and to the antibody designated TR105 (c-SN6j) therein [1].
Click here for help
No information available.
Summary of Clinical Use Click here for help
Carotuximab (using research code TRC105) is being evaluated in a number of Phase II clinical trials, against a range of solid tumour types. Click here to link to the Phase II carotuximab trials listed by