carotuximab   Click here for help

GtoPdb Ligand ID: 9098

Synonyms: c-SN6j | TRC-105 | TRC105
Compound class: Antibody
Comment: Carotuximab is an investigational, chimeric mouse/human anti-endoglin monoclonal antibody, with potential immunomodulatory and antineoplastic action.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. Protein BLAST analysis reveals 100% matches with peptides claimed in patent US8221753, and to the antibody designated TR105 (c-SN6j) therein [1].
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1. Theuer C, Vasquez M. (2012)
Endoglin antibodies.
Patent number: US8221753 B2. Assignee: Tracon Pharmaceuticals, Inc.. Priority date: 30/09/2009. Publication date: 17/07/2012.