tepilamide fumarate

Ligand id: 9770

Name: tepilamide fumarate

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 72.91
Molecular weight 243.11
XLogP 0.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
XP23829 has completed a Phase 2 clinical trial in patients with moderate-to-severe chronic plaque-type psoriasis (see NCT02173301). It has also been suggested as a treatment for relapsing-remitting multiple sclerosis, given approval of another MMF prodrug, dimethyl fumarate, for MS.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT02173301 A Study to Assess the Efficacy and Safety of XP23829 in Subjects With Moderate-to-Severe Chronic Plaque-Type Psoriasis Phase 2 Interventional XenoPort, Inc.