fluvoxamine

Ligand id: 7189

Name: fluvoxamine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 56.84
Molecular weight 318.16
XLogP 3.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Fluvoxamine acts as a nanomolar inhibitor of the σ1 receptor [4], and has been shown to reduce σ1-mediated inflammatory responses in human peripheral blood cells and in mouse models of inflammation and sepsis [2].