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Ligand id: 7189
View more information in the IUPHAR Pharmacology Education Project: fluvoxamine
Molecular properties generated using the CDK
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Inazu M, Takeda H, Ikoshi H, Sugisawa M, Uchida Y, Matsumiya T. (2001)
Pharmacological characterization and visualization of the glial serotonin transporter.
Neurochem. Int., 39 (1): 39-49. [PMID:11311448]
2. Rosen DA, Seki SM, Fernández-Castañeda A, Beiter RM, Eccles JD, Woodfolk JA, Gaultier A. (2019)
Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis.
Sci Transl Med, 11 (478). [PMID:30728287]
3. Tatsumi M, Groshan K, Blakely RD, Richelson E. (1997)
Pharmacological profile of antidepressants and related compounds at human monoamine transporters.
Eur. J. Pharmacol., 340 (2-3): 249-58. [PMID:9537821]
4. Yu LF, Zhang HK, Gunosewoyo H, Kozikowski AP. (2012)
From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design.
ACS Med Chem Lett, 3 (12): 1054-1058. [PMID:23641311]