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Synonyms: KB-003 | KB003
Compound class: Antibody
Comment: Lenzilumab is a fully human IgG1κ moncolonal antibody targeting granulocyte-macrophage colony-stimulating factor (GM-CSF), being investigated for its immunomodulatory potential.
Peptide sequences for this antibody are available from its IMGT/mAb-DB record.
BLAST peptide searches using the variable regions of the heavy and light chains of the antibody reveal exact matches with sequences submitted with patent US8075885 B2 .
|B-cell chronic lymphocytic leukemia||
|Phase 1 clinical candidate for CLL (see NCT02546284).|
|Clinical candidate for RA (maximum Phase 2).|
|Clinical candidate for asthma (maximum Phase 2).|