timolumab   Click here for help

GtoPdb Ligand ID: 9097

Synonyms: 8c10 | BTT-1023 | BTT1023 | r8c10 | SI-3106 | SI-636
Immunopharmacology Ligand
Compound class: Antibody
Comment: Tmolumab is a fully human anti-AOC3 (amine oxidase copper containing 3, VAP1) monoclonal antibody being investigated for its immunomodulatory action.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. Protein BLAST analysis reveals 100% matches with peptides claimed in patent US7897149, in particular with the recombinant fully human antibody BTT-1023 named therein [1].
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Immunopharmacology Disease
Disease X-Refs Comment References
Primary sclerosing cholangitis Orphanet: ORPHA171
Phase 2 clinical candidate for PSC.
Psoriasis Disease Ontology: DOID:8893
Completed Phase 1 clinical trial NCT00871598.
Rheumatoid arthritis Disease Ontology: DOID:7148
OMIM: 180300
Completed Phase 1 clinical trial NCT00851240.