Ligand id: 10475

Name: CS2164

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 86.47
Molecular weight 435.16
XLogP 4.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Deng M, Shi Y, Chen K, Zhao H, Wang Y, Xie S, Zhao J, Luo Y, Fang Z, Fan Y et al.. (2018)
CS2164 exerts an antitumor effect against human Non-Hodgkin's lymphomas in vitro and in vivo.
Exp. Cell Res., 369 (2): 356-362. [PMID:29864401]
2. Lu X-P, Li Z, Yu J, Ning Z. (2010)
Naphthamide Derivatives As Multi-Target Protein Kinase Inhibitors and Histone Deacetylase Inhibitors.
Patent number: US20100298358A1. Assignee: SHENZHEN CHIPSCREEN BIOSCIENCES, LTD.. Priority date: 22/05/2009. Publication date: 25/11/2010.
3. Zhou Y, Shan S, Li ZB, Xin LJ, Pan DS, Yang QJ, Liu YP, Yue XP, Liu XR, Gao JZ et al.. (2017)
CS2164, a novel multi-target inhibitor against tumor angiogenesis, mitosis and chronic inflammation with anti-tumor potency.
Cancer Sci., 108 (3): 469-477. [PMID:28004478]