Synonyms: Florafur® | FT-207 | FT207 | Ftorafur®
tegafur is an approved drug (EMA (2011))
Compound class:
Synthetic organic
Comment: Like capecitabine and floxuridine, tegafur is a prodrug of the chemotherapeutic agent 5-fluorouracil. It is orally active. The INN specifies tegafur as a racemic mixture of enantiomers. We show the molecule without specified stereochemistry to represent the mixture.
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References |
1. Engel D, Nudelman A, Tarasenko N, Levovich I, Makarovsky I, Sochotnikov S, Tarasenko I, Rephaeli A. (2008)
Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties. J Med Chem, 51 (2): 314-23. [PMID:18163551] |