Synonyms: Hiprex® | Mandelamine® | Urex®
methenamine is an approved drug (FDA (1967), UK (1989))
Compound class:
Synthetic organic
Comment: Methenamine is a heterocyclic organic compound. It is metabolised to formaldehyde, which acts as a nonspecific bactericidal agent. Methenamine is administered as the hippuric acid salt, methenamine hippurate (PubChem CID 21945).
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References |
1. De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP. (2013)
Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol, 83 (6): 1257-67. [PMID:23571415] |